All High on Life 2 – Gatlian Guns: A Complete List and Best Upgrades Guide

If you’ve been bouncing around the universe in High on Life 2, you know one thing for sure: the guns aren’t just tools—they’re full-blown personalities. Squanch Games has outdone themselves, delivering an arsenal of sentient, snarky, and sometimes downright rude weapons that feel more like party guests than firepower.

All High on Life 2 - Gatlian Guns: A Complete List and Best Upgrades Guide All High on Life 2 - Gatlian Guns: A Complete List and Best Upgrades Guide

Whether you’re revisiting fan favorites or hunting down the shiny new Gatlians, here’s a deep dive into all the weapons and how to snag them.

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Returning Favorites: The Classics You Can’t Forget

The sequel brings back several Gatlians from the original game and the High On Knife DLC, each with their own unique flair. These are the must-have starters if you want to dominate in close-range chaos or unleash unpredictable mayhem.

  • Gus (Voiced by JB Smoove)
    Type: Shotgun
    Abilities: Close-range powerhouse, disc launcher that ricochets off walls.
    Where to Find: Starting weapon.
    Pro Tip: Upgrading the Slug Chunker for 1,500 Pesos is a game-changer for boss fights. The ricochet discs are perfect for hitting enemies hiding behind corners.
  • Sweezy (Voiced by Betsy Sodaro)
    Type: Crystal Needler
    Abilities: Fires detonation crystals, perfect for crowd control or explosive setups.
    Where to Find: Starting weapon.
    Pro Tip: Keep an eye out for hidden cosmetic upgrades that make your Sweezy not just deadly, but stylish.
  • Creature (Voiced by Tim Robinson)
    Type: Swarm Launcher
    Abilities: Launches its own offspring to swarm and distract enemies.
    Where to Find: Unlocked during the Jeppy Pickup Mission.
  • B.A.L.L.
    Type: Pinball-inspired Weapon
    Abilities: Treats the battlefield like a pinball machine, bouncing projectiles off walls to deal damage unpredictably.
    Where to Find: Open-world collectible from the High On Knife DLC returnees.

New Gatlians You Need to Meet

High on Life 2 isn’t just nostalgia—it’s packed with fresh personalities that bring new combat dynamics.

  • Travis (Voiced by Ken Marino)
    Type: Dual SMG
    Abilities: Rapid-fire chaos, known for his “toxic” banter mid-battle.
    Where to Find: Story progression.
  • Jan
    Type: Dual SMG Partner
    Abilities: Complements Travis in synchronized attacks, doubling your DPS.
  • Sheath
    Type: Melee/Defensive
    Abilities: Offers a mix of offense and defense, perfect for switching up your combat style when ranged fights get tricky.
  • Bowie
    Type: Versatile Weapon
    Abilities: Balanced tool for most encounters, can adapt to different combat situations.
  • Shoot-O
    Type: Heavy Artillery
    Abilities: Progressive unlock through the campaign, designed for maximum battlefield impact.

Melee and Special Tools

Knifey makes a triumphant return, and this time it’s even more dangerous. With a new chainsaw mode, he can tear through environmental obstacles, clearing paths while cutting down enemies. If you’ve ever wanted a knife that doubles as a demolition tool, Knifey has you covered.

Tips to Upgrade and Customize Your Gatlians

High on Life 2 rewards exploration, and that includes leveling up your weapons and cosmetics. Here are some quick tips to get the most out of your Gatlians:

  • Gus Upgrades: Focus on Slug Chunker for max damage against bosses.
  • Cosmetics: Sweezy, Gus, Sheath, and others have unique cosmetic items hidden in chests across the biomes. Collecting them not only looks cool but sometimes boosts performance stats.
  • Performance Boosts: Don’t ignore open-world collectibles. They often grant small but meaningful upgrades like fire rate boosts or increased ammo capacity.
WeaponTypeUnique AbilityUnlock LocationRecommended Upgrade
GusShotgunRicochet disc launcherStarting weaponSlug Chunker (1,500 Pesos)
SweezyCrystal NeedlerDetonating crystalsStarting weaponHidden cosmetics
CreatureSwarm LauncherSummons offspringJeppy Pickup MissionAttack speed boost
B.A.L.L.Pinball WeaponRicocheting projectilesOpen-world collectibleRange extension
Travis & JanDual SMGRapid-fire comboStory progressionFire rate enhancement
SheathMelee/DefensiveBalanced offense & defenseStory missionArmor boost
BowieVersatileAdaptable in combatMain storyDamage upgrade
Shoot-OHeavy ArtilleryHigh damageCampaign progressionAmmo capacity

 

High on Life 2: Essential Gun Upgrades for Every Bounty Hunter

Since High on Life 2 dropped on February 13, 2026, it’s been a whirlwind of chaotic sci-fi fun, blending Rick and Morty–style humor with wild, inventive gameplay. Squanch Games didn’t just bring back the original’s wacky arsenal—they cranked everything up: sentient alien weapons, a skateboard traversal system that actually makes you feel like a stunt hero, and more ways to spend your Pesos than you’ll know what to do with.

But let’s be real: you can’t just skate around and hope for the best. If you want to survive the pharmaceutical conspiracy, insane bounty missions, and literally grinding rails at high speed, you need the right upgrades. Here’s my take on the best gun and gear mods to focus on, based on personal gameplay, Reddit chatter, and some good old-fashioned testing.

All High on Life 2 - Gatlian Guns: A Complete List and Best Upgrades Guide

Top-Tier Upgrades You Can’t Ignore

These are the mods that instantly improve your combat efficiency and make the early game feel less punishing.

Gus – Vacuum Mod
Why it rocks: Gus is your shotgun powerhouse, but it only shines at close range. The Vacuum Mod basically pulls smaller enemies toward you, so you can mow them down before they even touch you. Seriously, it’s like a magnetic force for chaos.
My take: Using this in dense fights feels so satisfying. You literally pull mobs to your doom.

Travis & Jan – Magazine Expansion
Why it matters: These dual-wielders hit hard and have crazy range, but the shared magazine is tiny. Expanding it is a must for keeping up sustained DPS.
Personal note: Nothing beats the feeling of emptying both barrels on a horde without hitting the reload panic.

Health & Shield Boosts (Jorb’s Shop)
Why it’s critical: Before stacking your firepower, beef up your base survivability. Later bounties spike enemy density like a caffeine overdose, and trust me—you don’t want to be caught under fire with low health.
Pro tip: Always visit Jorb first thing after unlocking a new area.

Advanced Combat Mods for Big Battles

Once your basics are covered, these mods elevate your combat strategy, making large encounters way more manageable.

Sweezy – Auto-Detonation Mod
Turns her from “meh” to explosive genius. The needles now detonate automatically, making Sweezy perfect for crowd control or surprise ambushes.

Creature – Minion Lifesteal
The ultimate sustain weapon. Creature’s minions heal you on kill, which is insanely useful for prolonged fights without constantly stopping to scavenge health.

Bowie – Charge Shot / Zoom Stabilizer
Bowie is your sniper-bow hybrid, and these mods let you pick off high-value targets before they get anywhere near you. Perfect for a strategic, high-ground player like me.

WeaponRecommended ModWhy It’s Useful
SweezyAuto-DetonationExplosive AoE for crowd control
CreatureMinion LifestealSustain and survivability
BowieCharge Shot/ZoomLong-range precision

Traversal and Utility: Don’t Sleep on Mobility

High on Life 2 isn’t just about pew-pew. Traversal matters—and the skateboard system is a game-changer.

Skateboard – Rail Grind Speed & Attack Mod
Grinding rails isn’t just cool; it’s combat-effective. Some mods let you attack while grinding, which is essential for arenas with vertical fights or moving enemy waves.

Jetpack – Fuel Capacity
More fuel = more time raining destruction from above. I cannot stress this enough. Bounty fights often have you in multi-level arenas, and the extra airtime lets you dominate from above while chaos reigns below.

Where to Score These Upgrades

Upgrades aren’t random drops—they have a system:

  • Jorb’s Shop (Quarters): Early-game essentials like health and weapon-specific mods. Your first stop after unlocking new gear.
  • The Mall Shop: Great for secondary health boosts, general utility, and situational mods. I always check this one after every major bounty.

All High on Life 2 - Gatlian Guns: A Complete List and Best Upgrades Guide

My Personal Favorites

After grinding bounties and experimenting with all weapons:

  1. Travis & Jan – nothing beats the firepower-to-fun ratio.
  2. Creature – lifesteal makes even dense mob waves manageable.
  3. Skateboard Attack Mod – because you feel like a parkour alien assassin.

Honestly, High on Life 2 rewards players who experiment. Don’t just follow guides—try combinations that fit your style.

Quick Tips for Bounty Hunters

– Prioritize survivability first, then raw damage.
– Upgrade traversal mods early—you’ll save hours on annoying backtracking.
– Mix weapons: one for crowd control, one for long-range, and one for pure chaos.
– Keep an eye on enemy type: some bosses are susceptible to AoE mods, others punish close-range shooters.

High on Life 2 isn’t just about pew-pew—it’s about how you play the chaos. Upgrade smart, pick your favorites, and the Pesos will rain down almost as fast as your bullets.

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